Antibacterial activity of murraya koenigii pdf
A total of three carbazole alkaloids and essential oil from the leaves of Murraya koenigii (Rutaceae) were obtained and examined for their effects on the growth of five antibiotic resistant pathogenic bacteria and three tumor cell lines (MCF-7, P 388 and Hela). Murraya koenigii, an indigenous herb with antimicrobial and antioxidant properties, can be best utilized as a food preservative which not only improve the storage quality of food items but also help to overcome the safety issues associated with synthetic food preservatives.
Title : ANTIBACTERIAL AND CYTOTOXIC ACTIVITIES OF MURRAYA KOENIGII Abstract : Crude ethanol extract of the leaves of Murayya koenigii (KAIDARYA) and the chloroform soluble fraction showed promising antibacterial activity against almost all of the tested bacteria. In the contact toxicity bioassay, lemongrass oil at a concentration of 0.15 g/l caused 100 % mortality and the number of eggs laid was zero. Antibacterial activity of different solvent extracts of leaves and water extract of stem (branch) and leaves of Murraya koenigii were found effective against bacterial species strains such as Bacillus licheniformis, Bacillus aureus, Eschericia coli. In our preliminary screening, the n-hexane, ethyl acetate and dichloromethane soluble fractions of the crude methanolic extract of Murraya koenigii were subjected to antibacterial activity and brine shrimp lethality bioassay. activity: Anti-inflammatory Activity of Murraya koenigii was studied in adult albino rats of either sex weighing between 120-150gms by Carrageenan Induced hind paw edema method [15,16].Animal were divided into four groups containing 6 animals per each. All the extracts were screened for its antibacterial activity using agar well diffusion method.
Search for medicinally valuable plants with antimicrobial activity is being emphasized due to increasing antibiotic resistance in bacteria. From Brine shrimp lethality assay, the LD of the sample of plant was found to be 125μg/mL. Antibacterial, antioxidant activity and brine shrimp lethality assay were studied. koenigii is a valued dietary plant used as spice since the ancient times for its characteristic aroma, and in medicine because of its possession of several bioactive compounds with health promoting properties. Gautam and Purobit (1974) reported that this essential oil exhibited a strong antibacterial and antifungal activity. Several potential and generally known as useful plants were selected in the study of Radical Scavenging Activity. anticancer, antiviral, antimalarial, antibacterial, antifeedent and antifertility activity of this plant (Rana 2008).
koenigii are useful in seasoning food items and preparing ready-to-eat foods.
The cytotoxic activity effect against MCF-7 cell line showed the CD 50 value less than 1 μg/ml, that present as very good activity. Aqueous extract of the leaves are reported to have antibacterial and nephroprotective action. The coarse material of Murraya koenigii was extracted with alcohol, benzene, acetone, chloroform using Soxhlet and macerated to form water extract. Many biological activities and antibacterial effects have been reported for Murraya koenigii plant of tannins and flavonoids [29-31].
The physical parameters of formulated gels like colour, homogeneity, pH, viscosity and spreadibility were evaluated. The Leaves and fruits are also a source of an essential oil which finds use as a fixative for heavy type of soap perfume.
Abstract: The present phytochemical investigations described the isolation of chemical constituents from the stem of indigenous plant Murraya koenigii(L.) Spreng which is commonly known as curry plant. study the antifungal and antibacterial activity of the leaves of Murraya koenigii. As the leaf and the seed extracts of Murraya koenigii exhibited significant antibacterial and antioxidative properties, they could be exploited for their therapeutic potential. The present study is the continuation of a program aimed at investigation on antioxidant activity of extracts from medicinal plants and to identify alternative natural and safe sources of food antioxidant especially from plant origin. Beneficial effects of Murraya koenigii leaves on antioxidant defense system and ultra structural changes of pancreatic beta-cells in experimental diabetes in rats. Mbata and co-workers 2006 also reported that aqueous extract of Camellia sinensis . Pathogenic strains of mycobacteria are resistant to most of the conventional antibiotics.
investigated for antibacterial and antifungal activity.
Hence, the present study was carried out to investigate anti-inflammatory and wound healing activities of Murraya koenigii fruits in rodents. For the current study, a rapid bioassay was used to evaluate compounds isolated from ethyl acetate extract of . Further, the study was extended to determine the antibacterial activity of copper oxide nanoparticle, which showed significant inhibitory activity in Salmonella typhii than the other bacterial species. The bioassay guided fractionation of the acetone extract of the fresh leaves of Murraya koenigii resulted in the isolation of three bioactive carbazole alkaloids, mahanimbine (1), murrayanol (2), and mahanine (3), as confirmed from their 1H and 13C NMR spectral data. The effects of Murraya koenigii leaves (MKL) on cognitive functions, total serum cholesterol level and brain cholinesterase activity in young and aged mice fed orally with a diet containing 2%, 4% and 8% w/w of MKL for 30 days consecutively, were investigated. The result of the acute toxicity showed that, the plant had LD50 of 4000mg.e'kg body weight, indicating non toxicity of the plant when consumed. 50 (inhibition concentration 50) of the ethanolic extracts of M Koenigii callus-stem-leaf were 47-78, and 116 μg/ml respectively.
The antibacterial (against E.coli&s.aureus) and antioxidant activities (DPPH) of peppermint oil were reported, where as the antibacterial activity of different extracts against the same bacterial strains was reported. The chemical composition of the fresh leaves of Murraya koenigii consists of volatile oil. Abstract: Curry plants (Murraya koenigii (L.) Spreng) plants recently cultivated in West Kalimantan have enormous potential as a plant producing essential oils and has antibacterial properties. The antibacterial activity of the extract was performed by disc diffusion assay using vancomycin (30 µg) as the standard. However, methanolic leaf extract exhibited greatest free radical scavenging activity. Summary& Conclusion The plant Murraya koenigii was collected from the area of karimnagar district, Telangana.
Curry leaves (Murraya koenigii), native to South Asian countries are commonly used as a food flavoring agent and known to have antioxidant, anti-inflammatory and antidiabetic activities.The objectives of this study were to investigate the anticancer and toxic effects of Curry Leaf Extracts (CLE) in Caco-2 and HepG2 cells and to assess the phytochemical content and antioxidant activities of CLE. The results acquired from this study points that polyphenol of Curry leaves (Murraya koenigii) had antibacterial property against Staphylococcus aureus when obtained at appropriate concentration. Murraya Koeinigii which is commonly known as the curry leaf plant and it was commonly used in all the curry and some other food items preparation in India for its aroma, it was high useful in the medicine, rich in vitamin A & E, useful for the hair growth and having some antimicrobial activity also [8-10]. The antifeedant and oviposition deterrent activity of hexane extract of Murraya koenigii leaves was evaluated at five different concentrations against the fourth instar larvae and gravid females of Spodoptera litura. The presence of phytochemicals, cytotoxicity, and antimicrobial and antioxidant activities were investigated. Murraya koenigii-mediated synthesis of silver nanoparticles and its activity against three human pathogenic bacteria.
The plant consists of a rich source of carbazole alkaloids.
The Leaves and fruits are also a source of an essential oil which finds use as a fixative for heavy sctivity of soap perfume. The fruit of bilimbi was shown to be potentially developed as antibacterial agents, especially for MDR strains. antioxidant activities of Murraya koenigii were carried out as well as the acute toxicity of the plant. organic solvents (methanol) showed better antimicrobial activity as compared to aqueous extracts Results of present study shows that leaves of Murraya koenigii having antimicrobial activity and can be used for natural antimicrobial agent. The present study aimed to examine the chemoprotective effect of Hydroethanolic Murraya koenigii leaves extract (HEMKLE) on murine skin carcinogenesis model.For the study, male LACA mice divided into four groups (n = 15 per group). A scrutiny of literature reveals some notable pharmacological activities of the plant.
Murraya koenigii is an aromatic more or less deciduous shrub or a small tree up to 6m in height and 15-40 cm in diameter found throughout India up to an altitude of 1,500m commonly in forests often as gregarious under-growths. Conclusion: The chloroform extract of Murraya koenigii and its sub fractions 2, 3,6, 7, 11, 32 and 37 possessed good anthelmintic activity and the isolation of active molecules is necessary for development of a novel anthelmintic. It is also called as curry leaf tree is commonly used as spice due to the aromatic nature of leaves. The herbal gels showed that formulations containing Murraya koenigii leaves extract have better antibacterial activity. Abstract: The present study was aimed for the evaluation of antioxidant activity and antifungal activity of essential oil and crude extracts (methanol and ethanol) of Murraya koenigii leaves. The present study was designed to screen the antimicrobial activity of Murraya koenigii Linn. In vitro antibacterial activity of biogenic gold nanoparticles from Murraya koenigii seed extract against pathogens associated with traumatic wound infections.
abstract Murraya koenigii, commonly growing in eastern Asia, is a herb that is highly valued for its medicinal potential; leaves of this plant, commonly known as Kurry Patta, are also used widely for culinary purpose, particularly in India.Medicinal value of the plant include antioxidant, antibacterial, anticancer, hypoglycemic, hypolipidemic and antidiabetic activity. Evaluation of antibacterial and cytotoxic activity of Artemisia nilagirica and Murraya koenigii leaf extracts against mycobacteria and macrophages. The antioxidant activity of these extracts was determined by DPPH (1, 1- Diphenyl- 2- picrylhydrazyl) assay. The present study deals with the synergistic antibacterial activity of Cynodon dactylon and Murraya koenigii. The MBC of water extract against ESβL + CR Pseudomonas aeruginosa showed the best antibacterial activity (12.5 mg/mL).